主要代表文章： （近五年，*通讯作者，#共同第一作者）

1. Fengyin Li^*, Xin Zhao^#, Yali Zhang, Peng Shao, Xiaoke Ma, William J. Paradee, Chengyu Liu, Jianmin Wang, and Hai-Hui Xue^*. (2021). T_FH cells depend on Tcf1-intrinsic HDAC activity to suppress CTLA4 and guard B-cell help function. PNAS, 118, e2014562118.

2. Fengyin Li, Bing He, Xiaoke Ma, Shuyang Yu, Rupali R. Bhave, Steven R. Lentz, Kai Tan, Monica L. Guzman, Chen Zhao^*, Hai-Hui Xue^*. (2017). Prostaglandin E1 and Its Analog Misoprostol Inhibit Human CML Stem Cell Self-Renewal via EP4 Receptor Activation and Repression of AP-1. Cell Stem Cell, 21, 1-15.

3. Shaojun Xing^#, Fengyin Li^#, Zhouhao Zeng^#, Yunjie Zhao, Shuyang Yu, Qiang Shan, Yalan Li, Farrah C Phillips, Peterson K Maina, Hank H Qi, Chengyu Liu, Jun Zhu, R Marshall Pope, Catherine A Musselman, Chen Zeng, Weiqun Peng*, Hai-Hui Xue*. (2016). Tcf1 and Lef1 transcription factors establish CD8+ T cell identity through intrinsic HDAC activity. Nat Immunol 17, 695-703.

4. Fengyin Li, Zhouhao Zeng, Shaojun Xing, Jodi A. Gullicksrud, Qiang Shan, Jinyong Choi, Vladimir P. Badovinac, Shane Crotty, Weiqun Peng & Hai-Hui Xue*. (2018). Ezh2 programs T_FH differentiation by integrating phosphorylation-dependent activation of Bcl6 and polycomb-dependent repression of p19Arf. Nat Commun 9, 1-18.

5. Cong Lv^#, Fengyin Li^#, Xiang Li^#, Yuhua Tian^#, Yue Zhang, Xiaole Sheng, Yongli Song, Qingyong Meng, Shukai Yuan, Liming Luan, Thomas Andl, XuFeng, Baowei Jiao, Mingang Xu, Maksim V. Plikus, Xing Dai, ChristopherLengner, Wei Cui, Fazheng Ren, Jianwei Shuai, Sarah E. Millar, Zhengquan Yu*. (2017). MiR-31 promotes mammary stem cell expansion and breast tumorigenesisby suppressing Wnt signaling antagonists. Nat Commun 8, 1-18.

6. Shuyang Yu^#, Fengyin Li^#, Shaojun Xing, Tianyan Zhao, Weiqun Peng, Hai-Hui Xue*. (2016). Hematopoietic and Leukemic Stem Cells Have Distinct Dependence onTcf1 and Lef1 Transcription Factors. J Biol Chem 291, 11148-11160.

7. Yue Zhang^#, Fengyin Li^#, Yongli Song, Xiaole Sheng, Kai Xiong, Lei Chen, Dequan Liu, Christopher Lengner, Lixiang Xue, Zhengquan Yu*. (2016). Numb and Numbl act to determine mammary myoepithelial cell fate,maintain epithelial identity, and support lactogenesis. FASEB J 30, 3474-3488.

8. Peng Shao^#, Fengyin Li^#, Jinyong Wang, Xia Chen, Chenyu Liu and Hai-Hui Xue* (2019). Cutting edge: Tcf1 instructs follicular helper cell differentiation by repressing blimp1 in response to acute viral infection. J Immunol, 203: 801-806.

9. Rahul Vijay^#, Jenna J Guthmiller^#, Alexandria J Sturtz, Fionna A Surette, Kai J Rogers, Ramakrishna R Sompallae, Fengyin Li, Rosemary L Pope, Jo-Anne Chan, Fabian de Labastida Rivera, Dean Andrew, Lachlan Webb, Wendy J Maury, Hai-Hui Xue, Christian R Engwerda, James S McCarthy, Michelle J Boyle, Noah S Butler. (2020). Infection-induced plasmablasts are a nutrient sink that impairs humoral immunity to malaria. Nat Immunol 21, 790-801.

10. Xin Zhao, Peng Shao, Kexin Gai, Fengyin Li, Qiang Shan, Hai-Hui Xue. (2020). β-catenin and γ-catenin are dispensable for T lymphocytes and AML leukemic stem cells. eLife 9, e55360.

11. Qiang Shan^#, Zhouhao Zeng^#, Shaojun Xing, Fengyin Li, Stacey M Hartwig, Jodi A Gullicksrud, Samarchith P Kurup, Natalija Van Braeckel-Budimir, Yao Su, Matthew D Martin, Steven M Varga, Ichiro Taniuchi, John T Harty, Weiqun Peng, Vladimir P Badovinac*, Hai-Hui Xue*. (2017). The transcription factor Runx3 guards cytotoxic CD8⁺ effector T cells against deviation towards follicular helper T cell lineage. Nat Immunol 18, 931-939.

12. Jodi A. Gullicksrud, Fengyin Li, Shaojun Xing, Zhouhao Zeng, Weiqun Peng, Vladimir P. Badovinac, John T. Harty, Hai-Hui Xue*. (2017). Differential Requirements for Tcf1 Long Isoforms in CD8⁺ and CD4⁺ T Cell Responses to Acute Viral Infection. J Immunol 3, 911-919.

13. Yan Xiu, Qianze Dong, Qingchang Li, Fengyin Li, Nick Borcherding, Weizhou Zhang, Brendan Boyce, Hai-hui Xue*, Chen Zhao*. (2018). Stabilization of NF-KB-inducing kinase suppresses MLL-AF9–induced acute myeloid leukemia. Cell reports 2, 350-358.

14. Shaojun Xing, Peng Shao, Fengyin Li, Xudong Zhao, WooseokSeo, Justin C. Wheat, Selvi Ramasamy, Jianfeng Wang, Xiang Li, Weiqun Peng, Shuyang Yu, Chengyu Liu, Ichiro Taniuchi, David A. Sweetser, Hai-Hui Xue*. (2018). Tle corepressors are differentially partitioned to instruct CD8⁺ T cell lineage choice and identity. J Exp Med 8, 2211-2226.

15. Qi Yang, Fengyin Li, Christelle Harly, Shaojun Xing, Longyun Ye, Xuefeng Xia, Haikun Wang, Xinxin Wang, Shuyang Yu, Xinyuan Zhou, Maggie Cam, Hai-Hui Xue*, Avinash Bhandoola*. (2015). TCF-1 upregulation identifies early innate lymphoid progenitors in the bone marrow. Nat Immunol 16, 1044-1050.

16. Youn Soo Choi^#, Jodi A Gullicksrud^#, Shaojun Xing, Zhouhao Zeng, Qiang Shan, Fengyin Li, Paul E Love, Weiqun Peng, Hai-Hui Xue*, Shane Crotty*.(2015). LEF-1 and TCF-1 orchestrate T_FH differentiation by regulating differentiation circuits upstream of the transcriptional repressor Bcl6. Nat Immunol 16, 980-990.

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