中国科学技术大学生命科学学院免疫学研究所
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程民研究员
( 2020-05-26 )

  



程  民  研究员,硕导,2020年加入免疫所。附属第一医院分子医学实验室副主任。2001年毕业于山东大学,获学士学位;2010年毕业于中国科学技术大学,获博士学位;2010年至2012年于中国科学技术大学从事博士后研究。主要研究成果发表Cancer Research、Aging Cell、Immunity & Ageing、Cellular & Molecular Immunology等杂志,申请并获得国家发明专利授权12项。2010年获得“中国科学院王宽诚博士后工作奖”,2015年获得“第十六届安徽青年科技奖”,2017年入选“第十一批安徽省学术和技术带头人后备人选”,先后获得安徽省科技二等奖两项。

主要研究兴趣:

      肺脏区域免疫应答及其微生态调控;肿瘤细胞免疫治疗;循环肿瘤细胞检测新技术。


近期发表文章:

1.  Yongyan Chen# *, Xiaolei Hao, Ming Li, Zhigang Tian, Min Cheng *. UGRP1-modulated MARCO+ alveolar macrophages contribute to age-related lung fibrosis, Immunity & Ageing, 2023, 20:14

2.  Cheng Min# *; Chen Yongyan; Huang Dake; Chen Wen; Xu Weiping; Chen Yin;Shen Guodong; Xu Tingjuan; Shen Gan; Tian Zhigang; Hu Shilian *; Intrinsically altered lung-resident γδT cells control lung melanoma by producing interleukin-17A in the elderly, Aging Cell, 2020, 19(e13099).

3.  Cui KL, Mei XY, Cheng M *. Increased interleukin-17A-producing gammadeltaT cells predict favorable survival in elderly patients with LUAD and LUSC. J Cancer Res Clin Oncol 2021.

4.   Cui KL# *, Hu SX#, Mei XY, Cheng M*. Innate Immune Cells in the Esophageal Tumor Microenvironment. Front Immunol 2021;12:654731.

5.   Shouxin Hu, Yanfang Zha, Wenwen Yang, Kele Cu* , and Min Cheng *. Dysregulation of NK and CD8+T Cells by the Microbiota Promotes the Progression of Lung Cancer. Journal of Immunology Research. Volume 2022, Article ID 7057089.

6.  Xinyu Mei#, Huan Li, Xinpeng Zhou, Min Cheng*, Kele Cui*. The emerging role of tissue-resident memory CD8+T lymphocytes in human digestive tract cancers. Frontiers in Oncology.2022

7.   Cheng M#*, Chen YY, Wang L, Chen W, Yang L, Shen GD, Xu TJ, Shen G, Tian ZG, Hu SL*. Commensal microbiota maintains alveolar macrophages with a low level of CCL24 production to generate anti-metastatic tumor activity. Scientific Reports. 2017,7:7471.

8.   Cheng M#*, Hu SL *. Lung-resident γδT cells and their roles in lung diseases. Immunology.2017,151:375-384.

9.    Cheng M#, Qian LT, Shen GD, Bian G, Xu TJ, Xu WP, Shen G, Hu SL*. Microbiota modulate tumoral immune surveillance in lung through a γδT17 immune cell-dependent mechanism. Cancer Research. 2014, 74(15):4030-4041.

10.   Cheng M#, Chen YY, Zou DH*, Shen GD, Bian G, Shen G, Hu SL*. The clinical utility of circulating tumor cells in breast cancer patients: detection by a quantitative assay of h-MAM gene expression.Int J Biol Markers.2014,29 (3): e268-e278.

11.    Cheng M#, Chen YY, Xiao WH, Sun R, Tian ZG*. NK cell-based immunotherapy for malignant diseases. Cellular & Molecular Immunology. 2013,10(3):230-252.

12.    Cheng M#, Fei BZ, Zheng XD, Chen YY, Sun R, Wei HM, Tian ZG*. A new reliable bioassay for determining the biological activity of human interleukin-12 by using human NK cell line NKG cells. International Immunopharmacology. 2012,13: 109–113.

13.   Cheng M#, Zhang J, Jiang W, Chen YY, Tian ZG*. Natural killer cell lines in tumor immunotherapy. Frontiers of Medicine. 2012, 6(1): 56–66.

14.   Cheng M#, Ma J, Chen YY, Zhang JH, Zhao WD, Zhang J, Wei HM, Ling B, Sun R, Tian ZG*.Establishment, Characterization and Successful Adaptive Therapy against Human Tumors of NKG Cell, a New Human NK Cell Line.Cell Transplantation. 2011, 20, 1731–1746.

15.   Cheng M#, Chen YY, Yu XQ, Tian ZG, Wei HM*. Diagnostic utility of LunX mRNA in peripheral blood and pleural fluid in patients with primary non-small cell lung cancer. BMC Cancer2008, 8:156.


 

 


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