白丽教授

生命科学学院

电子邮箱

瀚海星云BBS

CMI杂志

中国科学技术大学

首页教授风采教授风采

白丽教授

( 2020-05-26 )

白丽 教授，博导，2010年加入免疫所。2001年毕业于华中科技大学生物系，获理学学士学位；2006年毕业于华中科技大学生物物理专业，获理学博士学位；2006至2010年在霍华德休斯医学研究所，芝加哥大学从事博士后研究。主要研究成果分别发表在Cell Metab、PNAS、Nat Commun、Cell Mol Immunol和J Immunol等期刊上，获Faculty of 1000好评和推荐。

主要研究兴趣：NKT细胞的免疫代谢调控及与代谢性炎症和肿瘤的关系。

1.Fu Sicheng^#, He,Kaixin Tian Chenxi, Sun Hua, Zhu Chenwen, Bai Shiyu, Liu Jiwei, Wu Qielan, Xie Di, Yue Ting, Shen Zhuxia, Dai Qingqing, Yu Xiaojun, Zhu Shu, Liu Gang, Zhou Rongbin, Duan Shengzhong, Tian Zhigang, Xu Tao, Wang Hua *, Bai Li *. Impaired lipid biosynthesis hinders anti-tumor efficacy of intratumoral iNKT cells. Nature Communications, 2020 Jan 23.

2.Wang L^#, Liu Z^#, Wang L, Wu Q, Li X, Xie D, Zhang H, Zhang Y, Gu L, Xue Y, Yue T, Liu G, Ji W, Wei H, Xu T, Bai L*. Spatial distribution of IL4 controls iNKT cell-DC crosstalk in tumors. Cell Mol Immunol. 2019 Jun 3.

3.Fu S^#, Zhu S^#, Tian C, Bai S, Zhang J, Zhan C, Xie D, Wang L, Li Z, Li J, Zhang H, Zhou R, Tian Z, Xu T, Bai L*.Immunometabolism regulates TCR recycling and iNKT cell functions.Sci. Signal.2019 Feb26.

4.Xue R^#, Zhang H^#, Pan J, Du Z, Zhou W, Zhang Z, Tian Z, Zhou R, Bai L*. Peripheral Dopamine Controlled by Gut Microbes Inhibits Invariant Natural Killer T Cell-Mediated Hepatitis. Front Immunol. 2018 Oct 17;9:2398.

5.Chen Z, Zhu S, Wang L, Xie D, Zhang H, Li X, Zheng X, Du Z, Li J, Bai L*. Memory Follicular Helper Invariant NKT Cells Recognize Lipid Antigens on Memory B Cells and Elicit Antibody Recall Responses.J Immunol. 2018 May 1;200(9):3117-3127.

6.Zhu S, Zhang H, Bai L*. NKT cells in liver diseases.Front Med. 2018 Jun;12(3):249-261.

7.Zhang HM#, Xue RF#, Zhu SS, Fu SC, Chen ZL, Zhou RB, Tian ZG, Bai L*. M2-specific reduction of CD1d switches NKT cell-mediated immune responses and triggers metaflammation in adipose tissue. Cellular & Molecular Immunology. 2018 May;15(5):506-517.

8.Zhu SS^#, Zhang JQ^#, Zhang L, Ma WT, Man N, Liu YM, Zhou W, Lin J, Wei PF, Jin PP, Zhang YJ, Hu Y, Gu EW, Lu XF, Yang ZL, Liu XS*, Bai L*, Wen LP*. Inhibition of Kupffer Cell Autophagy Abrogates Nanoparticle-Induced Liver Injury. Advanced Healthcare Materials. 2017 May; 6(9).

9.Xie D，Zhu SS，Bai L*. Lactic acid in tumor microenvironments causes dysfunction of NKT cells by interfering with mTOR signaling. Science China Life Sciences，2016.12.05,(59):1290.

10.Bai L*^,#, Deng SL^#, Reboulet R^#, Mathew R , Teyton L, Savage PB , Bendelac A*. Natural killer T (NKT)-B-cell interactions promote prolonged antibody responses and long-term memory to pneumococcal capsular polysaccharides. Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):16097-102.