周荣斌教授

生命科学学院

电子邮箱

瀚海星云BBS

CMI杂志

中国科学技术大学

首页教授风采教授风采

周荣斌教授

( 2020-05-27 )

实验室主页：http://lirst.ustc.edu.cn/

周荣斌 教授，博导，2011年进入免疫所。入选“国家级人才项目”，基金委创新群体、杰青和科技部重点研发计划项目负责人生命科学与医学部部长、基础医学院执行院长。主持基金委创新群体、科技部重点研发计划等项目。任Cell Mol Immunol编委、中国免疫学会常务理事、青年工作委员会主任委员和安徽省免疫学会副理事长。以第一/通讯作者在Nature、Cell、NatRevImmunol、NatImmunol、Immunity等发表论文20余篇。第一完成人获国家自然科学二等奖、中国优秀青年科技人才奖、中国青年科技奖、谈家桢生命科学创新奖等。

主要研究兴趣：无菌性炎症中的固有免疫识别、调控及疾病干预研究。

主要代表论文：

1. Xu Y, Yan J, Tao Y, Qian X, Zhang C, Yin L, Gu P, Liu Y, Pan Y, Tang R, Jiang W, Zhou R. Pituitary hormone α-MSH promotes tumor-induced myelopoiesis and immunosuppression. Science. 2022 Sep 2;377(6610):1085-1091. doi: 10.1126/science.abj267

2. Wang X, Cai J, Lin B, Ma M, Tao Y, Zhou Y, Bai L, Jiang W, Zhou R. GPR34-mediated sensing of lysophosphatidylserine released by apoptotic neutrophils activates type 3 innate lymphoid cells to mediate tissue repair. Immunity.2021 Jun 8;54(6):1123-1136.e8

3. Huang Y, Wang H, Hao Y, Lin H, Dong M, Ye J, Song L, Wang Y, Li Q, Shan B, Jiang Y, Li H, Shao Z, Kroemer G, Zhang H, Bai L, Jin T, Wang C, Ma Y, Cai Y,Ding C, Liu S, Pan Y, Jiang W, Zhou R. Myeloid PTEN promotes chemotherapy-induced NLRP3 inflammasome activation and antitumor immunity. Nat Cell Biol. 2020 Jun;22(6):716-727.

4. Gong T, Liu L, Jiang W, Zhou R. DAMP-sensing receptors in sterile inflammation and inflammatory diseases. Nat Rev Immunol. 2020 Feb;20(2):95-112.

5. Liu L, Gong T, Tao W, Lin B, Li C, Zheng X, Zhu S, Jiang W, Zhou R. Commensal viruses maintain intestinal intraepithelial lymphocytes via noncanonical RIG-I signaling. Nat Immunol. 2019 Dec;20(12):1681-1691

6. Gong T, Zhou R. ApoC3: an 'alarmin' triggering sterile inflammation. Nat Immunol. 2020 Jan;21(1):9-11.

7. Yan Y, Jiang W, Liu L, Wang X, Ding C, Tian Z, Zhou R. Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome. Cell. 2015 Jan 15;160(1-2):62-73.

8. Wang X, Jiang W, Yan Y, Gong T, Han J, Tian Z, Zhou R. RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway. Nat Immunol. 2014 ;15(12):1126-33.

9. Yan Y, Jiang W, Spinetti T, Tardivel A, Castillo R, Bourquin C, Guarda G, Tian Z, Tschopp J, Zhou R. ω-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation. Immunity. 2013 Jun 27;38(6):1154-63.

10. Jiang H, He H, Chen Y, Huang W, Cheng J, Ye J, Wang A, Tao J, Wang C, Liu Q, Jin T, Jiang W, Deng X, Zhou R. Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders. J Exp Med 2017 Nov 6;214(11):3219-3238.