主要代表文章: 1. Jing Jin#,* Lin Bai#, Dongyao Wang#, Wei Ding, Zhuoxian Cao, Peidong Yan, Yunjia Li, Lulu Xi, Yuxin Wang, Xiaohu Zheng, Haiming Wei, Chen Ding, * Yi Wang *. SIRT3-dependent delactylation of cyclin E2 prevents hepatocellular carcinoma growth. EMBO Reports, 2023. (Impact Factor: 9.421) 2. Yunjia Li, Jing Jin,Yi Wang.* SIRT6 Widely Regulates Aging, Immunity, and Cancer. Front. Oncol., 06 April 2022. (Impact Factor: 5.738) 3. Jing Jin, Bin He, Xiaoyu Zhang, Hening Lin, * Yi Wang. * SIRT2 reverses 4-oxononanoyl lysine modification on histones. J. Am. Chem. Soc., 2016, 138 (38), pp 12304–12307. (Impact Factor: 16.383) 4. Yi Wang#, Jing Jin#, Matthew Wai Heng Chung#, Ling Feng, Hongyan Sun, Quan Hao. Identificationof the YEATS domain of GAS41 as a pH-dependent reader of histone succinylation. Proc Natl Acad Sci U S A. 2018, Feb 20. pii: 201717664. 5. Yi Wang, Yi Man Eva Fung, Weizhe Zhang, Bin He, Matthew Wai Heng Chung, Jing Jin, Jing Hu, Hening Lin, Quan Hao. De-acylation Mechanism by SIRT2 Revealed in an Intermediate Structure. Cell Chemical Biology, 2017. 16; 24(3): 339-345. 6. Xiucong Bao#, Yi Wang#, Xin Li#, Xiao-Meng Li#, Zheng Liu, Tangpo Yang, Chi Fat Wong, Jiangwen Zhang, Quan Hao, Xiang David Li. Identification of ‘erasers’ for lysine crotonylated histone marks using a chemical proteomics approach. eLife. 2014; 3: e02999. 7. Hong Jiang#, Saba Khan#, Yi Wang#, Guillaume Charron, Bin He, Carlos Sebastian, Jin tang Du, Ray Kim, Eva Ge, Raul Mostoslavsky, Howard C. Hang, Quan Hao & Hening Lin. SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine. Nature. 2013, 496, (110–113). 8. He Huang, Di Zhang, Yi Wang, Mathew Perez-Neut, Zhen Han, Y. George Zheng, Quan Hao & Yingming Zhao. Lysine benzoylation is a histone mark regulated by SIRT2. Nature Communications, 2018, v. 9 n. 1, p. 3374 9. Zhen Tong, Miao Wang, Yi Wang, David D. Kim, Jennifer K. Grenier, Ji Cao, Sushabhan Sadhukhan, Quan Hao, and Hening Lin. SIRT7 is an RNA-activated protein lysine deacylase. ACS Chem. Biol. 2016, DOI: 10.1021/acschembio.6b00954. 10. Yusheng Xie, Jingyan Ge, Haipeng Lei, Bo Peng, Huatang Zhang, Danyang Wang, Sijun Pan, Ganchao Chen, Lanfang Chen, Yi Wang, Quan Hao, Shao Q. Yao, Hongyan Sun. Fluorescent Probes for Single-Step Detection and Proteomic Profiling of Histone Deacetylases. J. Am. Chem. Soc., 2016, 138 (48), pp 15596–15604 11. Zhen Tong, Yi Wang, Xiaoyu Zhang, David D. Kim, Sushabhan Sadhukhan, Quan Hao, Hening Lin*. SIRT7 Is Activated by DNA and Deacetylates Histone H3 in the Chromatin Context. ACS Chem. Biol. 2016, 11, 742−747 12. Shrestha Ghosh, Baohua Liu, Yi Wang, Quan Hao, Zhongjun Zhou. Lamin A Is an Endogenous SIRT6 Activator and Promotes SIRT6-Mediated DNA Repair. Cell report. 2015, 1396–1406 13. Yi Wang, Yong-Xing He, Jiang Yu and Cong-Zhao Zhou*. Cloning, overproduction, purification, crystallization and preliminary X-ray diffraction analysis of yeast glutaredoxin Grx5. Acta Crystallographica Section F, 2009, ISSN 1744-3091 |