周次

教学时间

序号

教学内容

Part I An Introduction to Immunobiology

Chapter-1　 Basic Concepts in Immunology

1

2010-09-01

1

Section-1  The components and function of the immune system

Chapter -2 Innate Immunity

2

2010-09-08

2

Section-1 The front line of host defense

Section-2　 Pattern recognition in the innate immune system

3

2010-09-15

3

Section-3 The complement system and innate immunity

4

2010-09-29

4

Section-4 Induced innate responses to infection

5

中秋节放假

Part II　The Recognition of Antigen

Chapter-3 Antigen Recognition by B-cell and T-cell

6

2010-10-06

5

Section-1 Antigen

Section-2 The structure of a typical antibody molecule

Section-3 The interaction of the antibody molecule with

specific antigen

7

2010-10-13

6

Section-4 Antigen recognition by T cells

Chapter-4 The Generation of Lymphocyte Antigen

 Receptors

8

2010-10-20

7

Section-1 Primary immunoglobulin gene rearrangement

9

2010-10-27

8

Section-2 T-cell receptor gene rearrangement

Section-3 Structural variation in immunoglobulin constant regions

Chapter-5 Antigen Presentation to T lymphocytes

10

2010-11-03

9

Section-1 The generation of T-cell receptor ligands

11

2010-11-10

10

Section-2 The major histocompatibility complex and its functions

Part III　The Development of Mature

　　　　  Lymphocyte Receptor Repertoires

Chapter-6 Signaling Through Immune System

 Receptors

12

2010-11-17

11

Section-1 General principles of transmembrane signaling

Section-2 Antigen receptor signaling and lymphocyte activation

Chapter-7 The Development and Survival of

 Lymphocytes

13

2010-11-24

12

Section-1 Development of B lymphocytes

Section-2 T-cell development in the thymus

14

2010-12-01

13

Section-3 Positive and negative selection of T cells

Section-4 Survival and maturation of lymphocytes in peripheral

　　　　　 lymphoid tissues

Part IV　 The adaptive immune response

Chapter-8 T Cell-mediated Immunity

15

2010-12-08

14

Section-1　 Entry of naïve T cells and antigen-presenting cells

Into peripheral lymphoid organs.

Section-2　 Priming of naïve T cells by pathogen

-activated dendritic cells.

16

2010-12-15

15

Section-3　 General properties of effector T cells and their cytokine

Section-4　 T cell-mediated cytotoxicity

Section-5　 Macrophage activation by TH1 cells

Chapter-9 The Humoral Immune Response

17

2009-12-22

16

Section-1 B-cell activation and antibody production

18

2010-12-29

17

Section-2 The distribution and functions of immunoglobulin

 isotypes

Section-3 The destruction of antibody-coated pathogens via

Fc receptors

19-20

2011-01-

考试