理论教学大纲 大纲撰写者 傅斌清 彭慧 一、教学目标和基本要求(500字以内) 本课程是面对全校生物类专业的本科生和硕士生的英文专业课，目的是引领学生解读免疫的奥秘，了解免疫系统的主要成员及这些免疫细胞是如何运作帮助机体在抵抗病原体和各种疾病中的作用。通过课程的学习，可以拓宽学生的视野和增加医学免疫学相关的知识储备，培养学生的跨学科创新思维。 二、课程简介 中文：（500字以内） 免疫学属生命科学的前沿学科，是和人体健康和疾病关系最密切的学科之一，也是近年来发展最迅速、应用最广泛的学科之一。本课程将系统介绍免疫学基本概念和原理，以及一些疾病及其背后的免疫反应真相，并通过一些疾病的实例，“理论联系实际”的方式帮助学生理解免疫系统对人类健康维持和疾病发生的作用，了解免疫学理论和技术的运用对疾病诊断、预防和治疗等实际问题做出的重要贡献，用免疫学原理和观点去认识健康与疾病，提高学生对现代生命科学与人类健康的认知。 英文：(1000字符以内) Immunology is a fast developing and important front line subject in life sciences, and it is closely related to human health and diseases. Immunology is also the discipline that has the most rapid development in recent years. This course will introduce basic concepts and principles of immunology, and the mechanism and immune response to some diseases. Combining the actual cases and anecdotal evidence, this course introduces the basic principles and general theory of immuology, and explains the initiation and development of immune-related diseases and their underlying mechanisms in plain chapter and verse. This course is designed to help students understand functions of the immune system in the maintenance of health and the incidence of disease, know about the contribution of immune principles and techniques in diagnosis, prevention and therapy of diseases, and promote self-awareness of health and disease in scientific views. 三、教学重点、难点（500字以内） 教学重点：免疫系统的组成和功能 教学难点：不同免疫细胞介导的免疫应答过程 四、教材名称及主要参考书 教材： Janeway’s Immunobiology，9th Edition 参考书：How the immune system works, 5th Edition 五、课程章节主要内容及学时分配 Chapter 1 Basic Concepts in Immunology (2学时) 介绍免疫学的起源、发展历程与现状 Chapter 2 Innate Immunity: The First Lines of Defense （2学时） 介绍天然免疫成员及其在机体免疫反应中的重要作用 Chapter 3 The Induced Response of Innate Immunity (2学时) 天然免疫细胞参与的免疫反应 Chapter 4 Antigen Recognition by B-cell and T-cell Receptors (2学时) 获得性免疫成员B细胞和T细胞 Chapter 5 The Generation of Lymphocyte Antigen Receptors (2学时) 淋巴细胞抗原受体的产生 Chapter 6 Antigen Presentation to T Lymphocytes (2学时) T细胞接受抗原提呈 Chapter 7 Lymphocyte Receptor Signaling (2学时) 淋巴细胞受体信号 Chapter 8 The Development of B and T Lymphocytes (2学时) B细胞和T细胞的发育 Chapter 9 T-cell-Mediated Immunity (2学时) T细胞介导的免疫应答 Chapter 10 The Humoral Immune Response (2学时) 体液免疫应答 Chapter 11 Integrated Dynamics of Innate and Adaptive Immunity (2学时) 天然免疫和获得性免疫综合应答 Chapter 12 The Mucosal Immune System (2学时) 黏膜免疫 Chapter 13 Failures of Host Defense Mechanisms (2学时) 宿主防御机制 Chapter 14 Allergy and Allergic Diseases (2学时) 过敏和过敏反应 Chapter 15 Autoimmunity and Transplantation (2学时) 自身免疫病和移植免疫 Chapter 17 Pregnancy Immunology（2学时） 妊娠免疫 Chapter 18 Manipulation of the Immune Response (2学时) 免疫反应应用，免疫学原理在疾病诊断、预防和治疗中的应用 考试（2学时） | 
