Institute of Immunology, University of Science & Technology of China
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Molecular Immunology (Rui Sun's Lab)
 

Rui Sun

Professor, Institute of Immunology

School of Life Science

University of Science & Technology of China

 

EDUCATION

03/1978-12/1982: Bachelor of Medicine, Shanxi Medical University, China

09/1997-06/2000: M.S., Immunology, Normal Bethune Med Univ, Changchun, China.

 

RESEARCH EXPERIENCE

10/1985-03/2001:  Assistant/Associate/Full Professor, Shandong Acad Med Sci, China

09/1995-09/1996: Visiting Scientist, NCI, NIH, USA

03/2001–03/2002: Visiting Scientist, NCI, NIH, USA

04/2002–03/2006: Visiting Scientist, NIAAA, NIH, USA

06/2006–present:  Professor, Univ Sci Tech China, China

 

RESEARCH INTERESTS

1. Innate Immune Recognition of Natural KIller (NK) Cells

2. NK/NKT Cells in Liver Injury and Regeneration

 

SELECTIVE PUBLICATIONS

 1. Sun R, Park O, Horiguchi N, Kulkarni S, Jeong W-IL, Sun HY, Radaeva S and Gao B. STAT1  contributes to dsRNA inhibition if liver regeneration after partial hepatectomy in mice. Hepatology. 2006; 44: 955-966.

 2. Sun R, Gao B. Negative regulation of liver regeneration by innate immunity (natural killer cells/interferon-gamma). Gastroenterology. 2004 Nov;127(5):1525-39.

3. Sun R, Tian Z, Kulkarni S, Gao B. IL-6 prevents T cell-mediated hepatitis via inhibition of NKT cells in CD4+ T cell- and STAT3-dependent manners. J Immunol. 2004 May 1;172(9):5648-55.

 4. Sun R, Jaruga B, Kulkarni S, Sun HY and Gao B. IL-6modulates hepatocyte proliferation via inducytion of HCF/p21cip1: Regulation by SOCS3. Biochemical and Biophysical Research Communication. 2005; 338: 1943-1949

 5. Radaeva S, Sun S, Jaruga B, Nguyen VT, Tian Z, Gao B. Natural Killer Cells Ameliorate Liver Fibrosis by Killing Activated Stellate Cells in NKG2D- dependent and tumour necrosis factor-related apoptosis-inducing ligand-dependent manners. Ganstroenterology. 2006; 130: 435-452

 6. Jin Z, Sun R, Wei H, Gao Y, Chen Y, Tian Z. Natural killer T cells aggravate liver fibrosis of HBV transgenic mice via activating hepatic stellate cells. Hepatology 2010,49:xxx

 7. Jiang W, Sun R, Wei H, Zhou R, Tian Z. Toll-like receptor 9 activation aggravates Con A-induced hepatitis via promoting accumulation and activation of liver CD4+ NKT cells. J Immunol 2009; 182:3768-74

 

COMMUNICATION 

Business Phone Number: 0086-551-3607977

Fax Number: 0086-551-3600832

E-mail: sunr@ustc.edu.cn 

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